Police tell News Leader Nine a tractor trailer tire laying in the road is the cause of the wrecks.
Two cars hit the tire, and then a motorcycle did as well.
Chief Deputy Coroner Freeman Worley pronounced the driver of the motorcycle,William Eugene Nelson, 84, dead on the scene.
Investigations are still underway. Columbus Police said they do not know how the tire fell onto the roadway.
The drivers of the cars were not injured.